CD82 anticorps (C-Term)
Aperçu rapide pour CD82 anticorps (C-Term) (ABIN2789464)
Antigène
Voir toutes CD82 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- DYVQAQVKCC GWVSFYNWTD NAELMNRPEV TYPCSCEVKG EEDNSLSVRK
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Homologie
- Human: 100%, Yeast: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against CD82. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 267 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD82
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Autre désignation
- CD82
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Sujet
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This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
Protein Interaction Partner: GGT1, CD81, CD53, UBC, LGALS3BP, AMFR, VANGL1, IGSF8, ITGA3, NUP88, PTGFRN, ITGB2, ITGA4, ERBB3, CD4, ERBB2, CD63, ITGA6, HLA-DRA, HLA-DMB, HLA-DMA, ITGB1, EGFR, HBEGF, CANX, LRP1, CD19, ITGAL, HLA-DOB, CD46, CD151, CD9, RUVBL1, POLR2A, KAT5, CTNNB1, RUVB
Protein Size: 267 -
Poids moléculaire
- 29 kDa
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ID gène
- 3732
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NCBI Accession
- NM_002231, NP_002222
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UniProt
- P27701
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Pathways
- Signalisation p53
Antigène
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